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IgA vasculitis (IgAV) (Henoch-Schönlein Purpura)

What is IgA vasculitis?

IgA vasculitis (IgAV) also known as Henoch-Schönlein Purpura (HSP), is a form of vasculitis (vessel inflammation) which affects small blood vessels. Often times IgAV starts out as a rash on the legs which is purplish and raised. It may cause joint aches. Serious complications like involvement of the intestines and the kidney can also occur.

Who gets IgA vasculitis?

IgA vasculitis most often affects children but it can occur at any age.

What causes IgA vasculitis?

The exact cause of this disease is unknown but is related to your immune system. People may have a cold (upper respiratory infection) or a gastrointestinal illness just before they develop the disease. However, no virus or other infection has been identified as a cause of the disorder.

How is IgA vasculitis diagnosed?

The diagnosis is based on your symptoms and examination findings. Your doctor will run some blood tests to look for inflammation, evaluate kidney function and rule out other forms of vasculitis. A urine sample will be needed to evaluate for kidney involvement. A biopsy from the skin or kidney may be needed.

What is the treatment for IgA vasculitis?

Often times no treatment may be needed and the disease can resolve on its own. Sometimes if there is kidney or gut involvement, prednisone may be started.